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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Potential antihypertensive agents. Some guanidine derivatives

DI Barron, PMG Bavin, GJ Durant, IL Natoff…

文献索引：Barron,D.I. et al. J. Med. Chem., 1963 , vol. 6, p. 705 - 711

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被引用次数: 18

摘要

Treatment of hypertensive disorders has been revolutionized in recent years by the discovery and use of agents which inhibit the release of neurohormones from the postganglionic sympathetic nerve endings. The first compound discovered to have this effect was choline 2, 6-xylyl ether bromide'(I), which effectively blocks transmission at peripheral sympathetic nerve terminals but suffers from muscarinic side-effects. Subsequently, ...

4-氯-2,6-二甲基苯酚结构式

4-氯-2,6-二甲基苯酚

~%

1-[2-(4-Chloro-2,6-dimethylphenyloxy)ethyl]guanidine结构式

1-[2-(4-Chloro-...

(Methyl-cycloheptyl-amino)-acetonitril结构式

(Methyl-cyclohe...

~%

2-[2-[cycloheptyl(methyl)amino]ethyl]guanidine结构式

2-[2-[cyclohept...

N-环庚基甲胺结构式

N-环庚基甲胺

~%

2-[2-[cycloheptyl(methyl)amino]ethyl]guanidine结构式

2-[2-[cyclohept...

N-Methyl-N-cycloheptyl-aethylendiamin结构式

N-Methyl-N-cycl...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[2-[cycloheptyl(methyl)amino]ethyl]guanidine结构式

2-[2-[cyclohept...

N-甲基环辛胺结构式

N-甲基环辛胺

~%

2-[2-[cyclooctyl(methyl)amino]ethyl]guanidine结构式

2-[2-[cycloocty...

未登录结构式

~%

2-[2-[cyclooctyl(methyl)amino]ethyl]guanidine结构式

2-[2-[cycloocty...

N-Methyl-N-cyclooctyl-aethylendiamin结构式

N-Methyl-N-cycl...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[2-[cyclooctyl(methyl)amino]ethyl]guanidine结构式

2-[2-[cycloocty...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

苯酚结构式

~%

2-(2-phenoxyethyl)guanidine结构式

2-(2-phenoxyeth...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

硫酚结构式

~%

2-(2-phenylsulfanylethyl)guanidine结构式

2-(2-phenylsulf...

2,6-二甲基苯酚结构式

2,6-二甲基苯酚

~%

2-[2-(2,6-Dimethylphenoxy)ethyl]guanidine结构式

2-[2-(2,6-Dimet...

2-(2,6-DIMETHYLPHENOXY)ACETONITRILE结构式

2-(2,6-DIMETHYL...

~%

2-[2-(2,6-Dimethylphenoxy)ethyl]guanidine结构式

2-[2-(2,6-Dimet...

4-(2,6-dimethyl-phenoxy)-butane-nitrile结构式

4-(2,6-dimethyl...

~%

2-[4-(2,6-Dimethylphenoxy)butyl]guanidine结构式

2-[4-(2,6-Dimet...

2-(3-Chloropropoxy)-1,3-dimethylbenzene结构式

2-(3-Chloroprop...

~%

2-[4-(2,6-Dimethylphenoxy)butyl]guanidine结构式

2-[4-(2,6-Dimet...

2,6-二甲基苯酚结构式

2,6-二甲基苯酚

~%

2-[2-(2,6-dimethylphenoxy)propyl]guanidine结构式

2-[2-(2,6-dimet...

未登录结构式

~%

2-[2-(2,6-dimethylphenoxy)propyl]guanidine结构式

2-[2-(2,6-dimet...

2-(2,6-dimethylphenoxy)-1-propanamine结构式

2-(2,6-dimethyl...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[2-(2,6-dimethylphenoxy)propyl]guanidine结构式

2-[2-(2,6-dimet...

N-(2,6-二甲基苯)甲酰胺结构式

N-(2,6-二甲基苯)甲酰胺

~%

2-[2-(N,2,6-trimethylanilino)ethyl]guanidine结构式

2-[2-(N,2,6-tri...

N-Methyl-N-[2,6-dimethyl-phenyl]-aethylendiamin结构式

N-Methyl-N-[2,6...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[2-(N,2,6-trimethylanilino)ethyl]guanidine结构式

2-[2-(N,2,6-tri...

未登录结构式

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[4-(2,6-Dimethylphenoxy)butyl]guanidine结构式

2-[4-(2,6-Dimet...

对甲酚结构式

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

~%

2-[2-(4-methylphenoxy)ethyl]guanidine结构式

2-[2-(4-methylp...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

对氯苯酚结构式

~%

2-[2-(4-chlorophenoxy)ethyl]guanidine结构式

2-[2-(4-chlorop...

2,6-二甲基苯酚结构式

2,6-二甲基苯酚

~%

1,2-Diphenyl-3-[2-(2,6-dimethylphenyloxy)ethyl]guanidine结构式

1,2-Diphenyl-3-...

2-(2,6-DIMETHYLPHENOXY)ACETONITRILE结构式

2-(2,6-DIMETHYL...

~%

1,2-Diphenyl-3-[2-(2,6-dimethylphenyloxy)ethyl]guanidine结构式

1,2-Diphenyl-3-...

2,4,6-三甲酚结构式

2,4,6-三甲酚

氯乙腈结构式

~%

2-(异丙叉丙酮氧基)乙胺 1HCL结构式

2-(异丙叉丙酮氧基)乙胺 1HCL

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

2-萘酚结构式

~%

2-(2-naphthalen-2-yloxyethyl)guanidine结构式

2-(2-naphthalen...

N-(2-phthalimidoethyl)-2',6'-xylidine结构式

N-(2-phthalimid...

~%

2-[2-(2,6-dimethylanilino)ethyl]guanidine结构式

2-[2-(2,6-dimet...

N-(2,6-dimethylphenyl)-1,2-diaminoethane结构式

N-(2,6-dimethyl...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[2-(2,6-dimethylanilino)ethyl]guanidine结构式

2-[2-(2,6-dimet...

未登录结构式

~%

2-[3-(2,6-Dimethylphenoxy)propyl]guanidine结构式

2-[3-(2,6-Dimet...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

3-(2,6-Dimethyl-phenoxy)-propylamin结构式

3-(2,6-Dimethyl...

~%

2-[3-(2,6-Dimethylphenoxy)propyl]guanidine结构式

2-[3-(2,6-Dimet...

丙泊酚结构式

~%

2-[2-[2,6-di(propan-2-yl)phenoxy]ethyl]guanidine结构式

2-[2-[2,6-di(pr...

2-[2,6-Diisopropyl-phenoxy]-ethylamin结构式

2-[2,6-Diisopro...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[2-[2,6-di(propan-2-yl)phenoxy]ethyl]guanidine结构式

2-[2-[2,6-di(pr...

2',6'-二甲基乙酰苯胺结构式

2',6'-二甲基乙酰苯胺

~%

1-[2-(N-Ethyl-2,6-dimethylanilino)ethyl]guanidine结构式

1-[2-(N-Ethyl-2...

未登录结构式

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

1-[2-(N-Ethyl-2,6-dimethylanilino)ethyl]guanidine结构式

1-[2-(N-Ethyl-2...

二苯甲醇结构式

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

~%

1-[2-(Diphenylmethoxy)ethyl]guanidine结构式

1-[2-(Diphenylm...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

邻甲酚结构式

~%

2-[2-(2-methylphenoxy)ethyl]guanidine结构式

2-[2-(2-methylp...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

间甲酚结构式

~%

2-[2-(3-methylphenoxy)ethyl]guanidine结构式

2-[2-(3-methylp...

N-[3-(2-trifluoromethylphenothiazin-10-yl)propyl]amine结构式

N-[3-(2-trifluo...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]guanidine结构式

2-[3-[2-(triflu...

(2-氨基乙基)甲基(苯)胺 1HCL结构式

(2-氨基乙基)甲基(苯)胺 1HCL

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

1-[2-(Methylphenylamino)ethyl]guanidine结构式

1-[2-(Methylphe...

邻氯苯酚结构式

~%

2-[2-(2-chlorophenoxy)ethyl]guanidine结构式

2-[2-(2-chlorop...

2-(2-氯苯氧基)乙胺结构式

2-(2-氯苯氧基)乙胺

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

~%

2-[2-(2-chlorophenoxy)ethyl]guanidine结构式

2-[2-(2-chlorop...

1-萘酚结构式

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

~%

2-(2-naphthalen-1-yloxyethyl)guanidine结构式

2-(2-naphthalen...

S-甲基异硫脲硫酸盐结构式

S-甲基异硫脲硫酸盐

氯乙腈结构式

4-甲氧基苯酚(MEHQ)结构式

4-甲氧基苯酚(MEHQ)

~%

1-[2-(p-Methoxyphenoxy)ethyl]guanidine结构式

1-[2-(p-Methoxy...