Tetrahedron

A selective reductive amination of aldehydes by the use of Hantzsch dihydropyridines as reductant

T Itoh, K Nagata, M Miyazaki, H Ishikawa, A Kurihara…

文献索引：Itoh, Takashi; Nagata, Kazuhiro; Miyazaki, Michiko; Ishikawa, Hiroyuki; Kurihara, Ayako; Ohsawa, Akio Tetrahedron, 2004 , vol. 60, # 31 p. 6649 - 6655

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被引用次数: 98

摘要

Direct reductive amination of an aldehyde was carried out using a Hantzsch dihydropyridine as the reductant in the presence of a catalytic amount of scandium triflate. The reaction was highly selective towards aldehydes over ketones, and other reducible functional groups did not affect the reaction.