Multicomponent Synthesis and Biological Evaluation of a Piperazine-Based Dopamine Receptor Ligand Library

M Stucchi, P Gmeiner, H Huebner…

文献索引：La Spisa, Fabio; Feo, Alberto; Mossetti, Riccardo; Tron, Gian Cesare Organic Letters, 2012 , vol. 14, # 23 p. 6044 - 6047

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被引用次数: 2

摘要

... Volume: Page: ... ACS Medicinal Chemistry Letters. ... receptor bound to an antagonist was also crystallized,(13) leading to additional ways to substantiate a reliable pharmacophore model for the rationalization of the observed binding affinities and selectivities.(14). ...