Chemistry and biology of diazonamide A: second total synthesis and biological investigations
…, P Giannakakou, A O'Brate
文献索引:Nicolaou; Hao, Junliang; Reddy, Mali V.; Rao, Paraselli Bheema; Rassias, Gerasimos; Snyder, Scott A.; Huang, Xianhai; Chen, David Y.-K.; Brenzovich, William E.; Giuseppone, Nicolas; Giannakakou, Paraskevi; O'Brate, Aurora Journal of the American Chemical Society, 2004 , vol. 126, # 40 p. 12897 - 12906
As an especially unique target for chemical synthesis, diazonamide A has the potential to be constructed through a plethora of synthetic routes, each attended by different challenges and opportunities for discovery. In this article, we detail our second total synthesis of diazonamide A through a sequence entirely distinct from that employed in our first campaign, one whose success required the development of several special strategies and ...