Tetrahedron Letters

Direct arylation of benzoxazole C–H bonds with iodobenzene diacetates

P Yu, G Zhang, F Chen, J Cheng

文献索引：Yu, Peng; Zhang, Guangyou; Chen, Fan; Cheng, Jiang Tetrahedron Letters, 2012 , vol. 53, # 34 p. 4588 - 4590

被引用次数: 19

摘要

A Pd (OAc) 2-catalyzed direct arylation of benzoxazole C–H bonds has been achieved with iodobenzene diacetates as the arylation reagent in moderate to good yields. The procedure tolerates a series of functional groups, such as methoxy, nitro, cyano, chloro, and bromo groups.

~66%

~87%

~60%

~82%

~40%

~74%

~38%

~35%

~53%

~83%

~72%

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