Methanolysis of phosphoramidates with boron trifluoride-methanol complex

S Ryu, JA Jackson, CM Thompson

文献索引：Ryu, Seungmin; Jackson, John A.; Thompson, Charles M. Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 4999 - 5002

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被引用次数: 20

摘要

0 sodium phenoxide in THF. lS Phosphoramidothionates 3g-3j were prepared in 64-85% yield by reaction of the corresponding phosphorochloridothionate with the requisite amines! p-Nitrophenoxy S-methyl [(2S)-2-(car-bethoxy) pyrrolidinyl] phosphorothioates (6a/6b) were prepared by sequential reaction of the S-methyl phosphorodichloridate (5) with l-proline ethyl ester and p-nitrophenol. 1 The 1, 3, 2-oxazaphospholidin-2-one 8 was prepared by ...