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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Development of 2, 4-Diaminopyrimidines as Antimalarials Based on Inhibition of the S108N and C59R+ S108N Mutants of Dihydrofolate Reductase from …

…, J Vanichtanankul…

文献索引：Bliss, Edward A.; Griffin, Roger J.; Stevens, Malcolm F. G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2217 - 2228

全文：HTML全文

被引用次数: 85

摘要

... Journal of Medicinal Chemistry. ... Road, Bangkok 10400, Thailand. J. Med. Chem. , 2002, 45 (6), pp 1244–1252. DOI: 10.1021/jm010131q. Publication Date (Web): February 9, 2002. Copyright © 2002 American Chemical Society. ...

6-ethyl-5-(4-fluoro-phenyl)-pyrimidine-2,4-diyldiamine结构式

6-ethyl-5-(4-fl...

~99%

2,4-diamino-5-(4-fluoro-3-nitrophenyl)-6-ethylpyrimidine结构式

2,4-diamino-5-(...

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3-azidopyrimethamine结构式

3-azidopyrimethamine

~84%

乙胺嘧啶结构式

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乙胺嘧啶结构式

~%

N'-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]-N,N-dimethylmethanimidamide结构式

N'-[2-chloro-5-...

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2,4-Diamino-5-(3-amino-4-chloro-5-nitrophenyl)-6-ethylpyrimidine结构式

2,4-Diamino-5-(...

~%

N'-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]-N,N-dimethylmethanimidamide结构式

N'-[2-chloro-5-...

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3-azidopyrimethamine结构式

3-azidopyrimethamine

~%

N'-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]-N,N-dimethylmethanimidamide结构式

N'-[2-chloro-5-...

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N,N-二甲基甲酰胺二甲基缩醛结构式

N,N-二甲基甲酰胺二甲基缩醛

2,4-Pyrimidinediamine,5-(3-amino-4-chlorophenyl)-6-ethyl结构式

2,4-Pyrimidined...

~%

N'-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]-N,N-dimethylmethanimidamide结构式

N'-[2-chloro-5-...

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乙胺嘧啶结构式

~%

6-ethyl-5-(4-methoxyphenyl)pyrimidine-2,4-diamine结构式

6-ethyl-5-(4-me...

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2,4-Diamino-5-(3-amino-4-chloro-5-nitrophenyl)-6-ethylpyrimidine结构式

2,4-Diamino-5-(...

~%

6-ethyl-5-(4-methoxyphenyl)pyrimidine-2,4-diamine结构式

6-ethyl-5-(4-me...

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2,4-Pyrimidinediamine,5-(3-amino-4-chlorophenyl)-6-ethyl结构式

2,4-Pyrimidined...

乙酰氯结构式

~53%

N-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]acetamide结构式

N-[2-chloro-5-(...

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2,4-Diamino-5-(3-amino-4-chloro-5-nitrophenyl)-6-ethylpyrimidine结构式

2,4-Diamino-5-(...

~%

N-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]acetamide结构式

N-[2-chloro-5-(...

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乙胺嘧啶结构式

~%

N-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]acetamide结构式

N-[2-chloro-5-(...

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3-azidopyrimethamine结构式

3-azidopyrimethamine

~%

N-[2-chloro-5-(2,4-diamino-6-ethylpyrimidin-5-yl)phenyl]acetamide结构式

N-[2-chloro-5-(...

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乙胺嘧啶结构式

~96%

2,4-Diamino-5-(3-amino-4-chloro-5-nitrophenyl)-6-ethylpyrimidine结构式

2,4-Diamino-5-(...

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2,4-二氨基-6-硝基喹唑啉结构式

2,4-二氨基-6-硝基喹唑啉

~91%

2,4,6-喹唑啉三胺结构式

2,4,6-喹唑啉三胺

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3-azidopyrimethamine结构式

3-azidopyrimethamine

~%

2,4-Pyrimidinediamine,5-(3-amino-4-chlorophenyl)-6-ethyl结构式

2,4-Pyrimidined...

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乙胺嘧啶结构式

~%

2,4-Pyrimidinediamine,5-(3-amino-4-chlorophenyl)-6-ethyl结构式

2,4-Pyrimidined...

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