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A new solvent system (cyclopentyl methyl ether–water) in process development of darifenacin HBr

C Pramanik, K Bapat, A Chaudhari…

文献索引:Organic Process Research and Development, , vol. 16, # 10 p. 1591 - 1597

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被引用次数: 2

摘要

... significant quantity (3–5%) under almost all conditions and gets extracted into organic solvents even ... Herein we are reporting an efficient commercial process for darifenacin hydrobromide (1 ... 6 to CONH 2 was preferable in comparison to the one-step procedure (Boc deprotection ...