Synthesis of fluorine analogues of protoporphyrin

…, T Shinada, S Kinoshita, N Arimura, T Nagai…

文献索引：Ando, Akira; Shinada, Tetsuro; Kinoshita, Shinji; Arimura, Noriko; Nagai, Takabumi; et al. Journal of Fluorine Chemistry, 1989 , vol. 42, p. 293 - 298

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被引用次数: 4

摘要

Abstract With intention of obtaining a porphyrin derivative useful for diagnosis and therapy of cancer, fluorine analogues of protoporphyrin, in which the vinyl group (s) were replaced by difluorovinyl group (s), were synthesized by the reaction of the formylporphyrins with sodium chlorodifluoroacetate in the presence of triphenylphosphine.