Synthesis and biological properties of analogs of diprophylline

…, YV Strokin, BA Samura, PN Steblyuk

文献索引：Kremzer, A. A.; Strokin, Yu. V.; Samura, B. A.; Steblyuk, P. N. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 6 p. 407 - 411 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 6 p. 59 - 64

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摘要

As can be seen from the figures given, compounds (X),(XIV), and (XV) increased the duration of narcotic sleep, exhibiting a neuroleptic effect. Compound (XV) proved to be the most active, in doses of 50 and 75 mg/kg increasing the duration of sleep by 71.6% and 75, 6%. respectively on an average~