European journal of medicinal chemistry

Synthesis and biological evaluation of 2-[substituted acetyl] amino-5-alkyl-1, 3, 4-thiadiazoles

AK Shakya, GK Patnaik, P Mishra

文献索引：Shakya; Patnaik; Mishra European Journal of Medicinal Chemistry, 1992 , vol. 27, # 1 p. 67 - 71

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被引用次数: 13

摘要

Abstract Some new N-substituted acetyl derivatives of 2-amino-5-alkyl-1, 3, 4-thiadiazoles have been prepared and investigated for antihistaminic and spasmolytic activity on guine pig ileum. A few of the compounds showed encouraging effects. In addition, some of the compounds also showed anti-inflammatory activity.