The synthesis and reaction of spiro (oxolane-2, 2'-piperazine)-3', 6'-diones with N-bromosuccinimide in the presence or absence of water.

~%

~%

~%

~%

~58%

~58%

~%

~%

~%

~%

~%

~%

~%

~%

~%

~90%

~64%

~%

~%

~%

~%