Tetrahedron

An expedient synthesis of enantioenriched substituted (2-benzofuryl) arylcarbinols via tandem Rap–Stoermer and asymmetric transfer hydrogenation reactions

G Kumaraswamy, G Ramakrishna, R Raju, M Padmaja

文献索引：Kumaraswamy, Gullapalli; Ramakrishna, Gajula; Raju, Ragam; Padmaja, Mogilisetti Tetrahedron, 2010 , vol. 66, # 52 p. 9814 - 9818

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被引用次数: 19

摘要

An expedient synthesis of enantioenriched substituted (benzofuran-yl)-aryl and heteroaryl carbinols, is described. A key feature of this protocol is synthesis of functionally varied benzofuran scaffolds via a Rap–Stoermer reaction/catalytic asymmetric transfer hydrogenation (ATH) using substituted salicylaldehyde and α-haloaryl, heteroaryl ketones.