Tetrahedron letters

Baker's yeast reduction of 5-acetyl-2-isoxazolines synthesis of enantiomerically pure 2, 3-dihydroxy ketones and 1, 2, 4-triols

C Ticozzi, A Zanarotti

文献索引：Ticozzi, Calimero; Zanarotti, Antonio Tetrahedron Letters, 1988 , vol. 29, # 47 p. 6167 - 6170

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被引用次数: 21

摘要

Abstract: Saccharomy- cerevisiae reduces enantioselectively racemic 5-acetyl-2- isoxazolines to 5-ethanol-2-isoxazolines in high yields and high enantiomeric excess. Subsequent ring hydrogenolysis of the alcohols thus produced leads to enantiomerically pure 2, 3-dihydroxy ketones and 1, 2, 4-trials.