Molecules

Original TDAE strategy using propargylic chloride: rapid access to 1, 4-diarylbut-3-ynol derivatives

M Roche, T Terme, P Vanelle

文献索引：Roche, Manon; Terme, Thierry; Vanelle, Patrice Molecules, 2013 , vol. 18, # 2 p. 1540 - 1548

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被引用次数: 4

摘要

Abstract We report herein the first synthesis of propargylic alcohols using an organic reducing agent. Diarylbutynol derivatives are formed in moderate to good yields under mild conditions from the reaction of 1-(3-chloroprop-1-ynyl)-4-nitrobenzene with various aromatic aldehydes using tetrakis (dimethylamino) ethylene (TDAE) as reductant. Keywords: