Steroids. CXXXIV. 1 Derivatives of 17α-Ethylnyltestosterone and 17α-Ethynyl-19-nortestosterone

LH Knox, JA Zderic, JP Ruelas, C Djerassi…

文献索引：Knox,L.H. et al. Journal of the American Chemical Society, 1960 , vol. 82, p. 1230 - 1235

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被引用次数: 17

摘要

In recent years considerable attention has been devoted to chemical modification of the orally active progestational agent 17a-ethynyltestosterone2 in the hope of obtaining even more active compounds. Among the outstanding modifications leading to potentiated progestational activity have been replacement of the C-10 angular methyl group by hydrogen (17a-ethynyl-19-nortestosterone3 and 17a-ethynyl-A5 (lo)-estren-17@-ol-3- ...