Tetrahedron Letters

Sulfonium alkylation followed by 'click'chemistry for facile surface modification of proteins and tobacco mosaic virus

L Yi, J Shi, S Gao, S Li, C Niu, Z Xi

文献索引：Yi, Long; Shi, Jie; Gao, Shuang; Li, Shibo; Niu, Congwei; Xi, Zhen Tetrahedron Letters, 2009 , vol. 50, # 7 p. 759 - 762

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被引用次数: 16

摘要

Alkylsulfonium salts (ASS) have been shown to act as powerful alkylating agents. However, few studies have addressed the application of sulfonium salts to the modification of biomolecules such as nucleic acids and proteins. Since these large biomolecules play important roles in biological processes, a convenient and fast method for their modification is greatly needed. In this work, for the first time, we used a tandem method of sulfonium ...