Few reports appeared in the literature concerning the synthesis of 2-pyrrolidinyl methyl ketones [I]. The preparation of the naturally occurring alkaloid hygrine (1-methyl-2-acetonyl pyrrolidine) has been described [2]. In the present investigation, the synthesis of a series of some unknown (1-methyl-2-pyrrolidinyl)-methyl ketones (I-XIV) has been undertaken for evaluating their pharmacological potentialities in an attempt to establish a chemical- ...