Tetrahedron Letters

A novel TMSI-mediated synthesis of Hantzsch 1, 4-dihydropyridines at ambient temperature

G Sabitha, GSKK Reddy, CS Reddy, JS Yadav

文献索引：Sabitha, Gowravaram; Reddy, G.S. Kiran Kumar; Reddy, Ch. Srinivas; Yadav Tetrahedron Letters, 2003 , vol. 44, # 21 p. 4129 - 4131

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被引用次数: 284

摘要

The synthesis of various substituted Hantzsch 1, 4-dihydropyridines has been achieved using the classical Hantzsch procedure and modified Hantzsch conditions for the first time at room temperature in the presence of iodotrimethylsilane (TMSI) generated in situ in CH3CN, in excellent yields.