Tetrahedron

Copper-mediated trifluoromethylation of potassium alkynyltrifluoroborates with Langlois' reagent

SR Dubbaka, S Nizalapur, AR Atthunuri, M Salla…

文献索引：Dubbaka, Srinivas Reddy; Nizalapur, Shashidhar; Atthunuri, Azmi Reddy; Salla, Manohar; Mathew, Thresen Tetrahedron, 2014 , vol. 70, # 12 p. 2118 - 2121

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被引用次数: 14

摘要

Abstract Synthesis of trifluoromethylated acetylenes by copper-mediated trifluoromethylation of potassium alkynyltrifluoroborates with CF 3 radicals generated from NaSO 2 CF 3 and tert- butyl hydroperoxide (TBHP) is communicated. The trifluoromethylated acetylenes were obtained in good to moderate yields. The presented method tolerates a wide range of aromatic, heteroaromatic, and aliphatic potassium alkynyltrifluoroborates.