Ru-catalyzed cyclization of terminal alkynals to cycloalkenes

JA Varela, C González-Rodríguez…

文献索引：Varela, Jesus A.; Gonzalez-Rodriguez, Carlos; Rubin, Silvia G.; Castedo, Luis; Saa, Carlos Journal of the American Chemical Society, 2006 , vol. 128, # 30 p. 9576 - 9577

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被引用次数: 39

摘要

In conclusion, we have discovered a new Ru-catalyzed cyclization of terminal alkynals to give cycloalkenes. Under appropriate catalytic conditions, cycloisomerization to conjugated aldehydes may be observed. Both processes involve catalytic Ru vinylidenes. On the basis of the findings described herein, we envisage new possibilities of C−C bond formation catalyzed by transition metal vinylidenes. Research in this direction is currently underway.