In recent years, there has been increasing interest in thiazolo[3,2-a]pyrimidin-7-ones and pyrido[1,2-a]pyrimidin-2-ones because of their useful and important physiological properties. The thiazolo[3,2-a]pyrimidin-7-ones are present some useful and important biologically activities, such as antifungal and anti-inflammatory [1]. On the other hand, the pyrido[1,2-a]pyrimidin -2-ones are known to exhibit a broad range of interesting biological activities, including ...