Chinese Chemical Letters

A novel and convenient synthesis of thiazolo [3, 2-a] pyrimidin-7-ones and pyrido [1, 2-a] pyrimidin-2-ones using Vilsmeier reagent

YY Weng, LM Ying, QX Chen, WK Su

Index: Weng, Yi Yi; Ying, Lei Ming; Chen, Qi Xu; Su, Wei Ke Chinese Chemical Letters, 2012 , vol. 23, # 8 p. 911 - 914

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Abstract

In recent years, there has been increasing interest in thiazolo[3,2-a]pyrimidin-7-ones and pyrido[1,2-a]pyrimidin-2-ones because of their useful and important physiological properties. The thiazolo[3,2-a]pyrimidin-7-ones are present some useful and important biologically activities, such as antifungal and anti-inflammatory [1]. On the other hand, the pyrido[1,2-a]pyrimidin -2-ones are known to exhibit a broad range of interesting biological activities, including ...