Chemical Communications

Efficient and regioselective synthesis of functionalized pyrroles by cyclocondensation of 1, 3-dicarbonyl dianions with α-azidoketones

P Langer, I Freifeld

文献索引：Langer, Peter; Freifeld, Ilia Chemical Communications, 2002 , # 22 p. 2668 - 2669

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被引用次数: 1

摘要

Functionalized pyrroles and 2-alkylidenepyrrolidines are present in a number of pharmacologically relevant natural and unnatural products and represent useful synthetic intermediates. 2-Alkylidenepyrrolidines have been used as key intermediates during the synthesis of mitomycin antitumor antibiotics possessing antibacterial activity. 1 Functionalized pyrroles are building blocks of natural tetrapyrrole pigments, 2 such as porphobilinogen or bilirubin, and various other natural products and ...