Conversion of cyclooxygenase inhibitors into hydroxythiazole 5-lipoxygenase inhibitors
…, CDW Brooks, KI Hulkower, JB Bouska, RL Bell
文献索引：Kerdesky, Francis A.J.; Brooks, Clint D.W.; Hulkower, Keren I.; Bouska, Jennifer B.; Bell, Randy L. Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 2 p. 393 - 396
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Representative examples of NSAID cyclooxygenase inhibitors such as naproxen, ibufenac, ibuprofen, and butibufen have been transformed into 5-lipoxygenase inhibitors by replacement of the carboxylic acid moiety with a 4-hydroxythiazole group. ... NSAID cyclooxygenase ...
