Novel optically active 2-(pyrazol-1-yl) pyridines have been prepared using resolved the O- methyl ether of atrolactic acid as a source of the adjacent quaternary carbon stereocenter. Different regioisomers were formed selectively in the reaction of 2-hydrazinopyridines with the chiral 1, 3-diketone and in the nucleophilic substitution of 2-chloropyridines with the potassium salt of the chiral pyrazole. The second route gave 2-(pyrazol-1-yl) pyridines ...