Chinese Chemical Letters

An efficient and mild protocol for the synthesis of unsymmetrical ureas in the absence of catalyst and additives

R Hosseinzadeh, Y Sarrafi, N Aghili

文献索引：Hosseinzadeh, Rahman; Sarrafi, Yaghoub; Aghili, Nora Chinese Chemical Letters, 2010 , vol. 21, # 10 p. 1171 - 1174

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被引用次数: 2

摘要

A new practical method for the synthesis of unsymmetrical ureas was achieved by reaction of phenylurea with primary and secondary amines under neutral and mild condition in very good yields. The reaction took place in refluxing dioxane and does not require any catalyst or additives.