Heterocycles

Syntheses of carprofen, a carbazole-based non-steroidal anti-inflammatory agent

PS Manchand, DL Coffen, PS Belica, F Wong…

文献索引：Heterocycles, , vol. 39, # 2 p. 833 - 846

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被引用次数: 9

摘要

... Abstract. Syntheses of carprofen (6) have been achieved by two approaches from carbazole (11). In one, 2,9-diacetylcarbazole (12) and 2-acetylcarbazole (13) were chlorinated with trichloroisocyanuric acid (15) to give the 6-chloro derivatives (16) and (17), respectively. ...