Chemical and Pharmaceutical Bulletin

Microbial metabolism. Part 11. Metabolites of flutamide

W Herath, IA Khan

文献索引：Herath, Wimal; Khan, Ikhlas Ahmad Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 4 p. 562 - 564

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被引用次数: 6

摘要

The yeast culture, Rhodotorula mucilaginosa (ATCC 20129) transformed flutamide (1) to three metabolites: 4-nitro-3-(trifluoromethyl) aniline (2), 2-methyl-N-[4-amino-3- (trifloromethyl) phenyl] propanamide (3) and N-[4-amino-3-(trifluoromethyl) phenyl] acetamide (4). The structures were established by spectroscopic methods.