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Heterocyclization Reactions of 2-(2-Propynylthio)-4 (1H)-quinazolinone Derivatives when Treated with Electrophilic and Nucleophilic Reagents

…, VI Staninets, VV Pirozhenko, AN Chernega

文献索引:Zborovskii; Orysyk; Dobosh; Staninets; Pirozhenko; Chernega Chemistry of Heterocyclic Compounds, 2003 , vol. 39, # 8 p. 1099 - 1106

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被引用次数: 9

摘要

Abstract Reaction of the potassium salt of 2-thioquinazolin-4-one with propargyl halides leads to formation of 2-propargylthioquinazolin-4-one derivatives, which undergo heterocyclization when they are treated with electrophilic or nucleophilic reagents and, depending on the nature of the cyclization agent, leads to formation of tricyclic systems with angular or linear structure.