Tetrahedron

Bisphosphonate prodrugs: synthesis of new aromatic and aliphatic 1-hydroxy-1, 1-bisphosphonate partial esters

…, E Guenin, E Migianu, D Lutomski, M Lecouvey

文献索引：Monteil, Maelle; Guenin, Erwann; Migianu, Evelyne; Lutomski, Didier; Lecouvey, Marc Tetrahedron, 2005 , vol. 61, # 31 p. 7528 - 7537

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被引用次数: 27

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Methods for the preparation of various 1-hydroxy-1,1-bisphosphonate partial esters were developed. They were obtained from (alkyl or phenyl) bis(trimethylsilyl) phosphite and aromatic or aliphatic acid chlorides, followed by methanolysis. ... Herein, we will present the extension of this ...