Synthesis and Crystal Structure of Two Diflunisal Carboxamides

G Zhong, H Hu, C Xia, J Jiang, T Chen

文献索引：Zhong, Guang-Xiang; Hu, Hong-Dan; Xia, Chun-Nian; Jiang, Jian-Song; Chen, Ting-Ting Journal of Chemical Crystallography, 2010 , vol. 40, # 9 p. 735 - 739

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被引用次数: 2

摘要

Abstract The title compounds, 2′, 4′-difluoro-4-[(4-methylbenzoyl) oxy]-N-[4-nitro-3- (trifluoromethyl) phenyl]-[1, 1′-biphenyl]-3-carboxamide 2a and 2′, 4′-difluoro-4-[(4- chlorobenzoyl) oxy]-N-[4-nitro-3-(trifluoromethyl) phenyl]-[1, 1′-biphenyl]-3-carboxamide 2b, synthesized from diflunisal, a registered anti-inflammatory drug, via amidation of carboxlic acid and esterification of phenolic hydroxy group and recrystallized from ...