Abstract The title compounds, 2′, 4′-difluoro-4-[(4-methylbenzoyl) oxy]-N-[4-nitro-3- (trifluoromethyl) phenyl]-[1, 1′-biphenyl]-3-carboxamide 2a and 2′, 4′-difluoro-4-[(4- chlorobenzoyl) oxy]-N-[4-nitro-3-(trifluoromethyl) phenyl]-[1, 1′-biphenyl]-3-carboxamide 2b, synthesized from diflunisal, a registered anti-inflammatory drug, via amidation of carboxlic acid and esterification of phenolic hydroxy group and recrystallized from ...