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Tetrahedron letters

Novel [1, 3]-migration of methyl group in imidazo [4, 5-c] quinoline

T Kuroda, F Suzuki

文献索引:Kuroda, Takeshi; Suzuki, Fumio Tetrahedron Letters, 1992 , vol. 33, # 15 p. 2027 - 2028

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被引用次数: 5

摘要

Abstract In synthetic studies of imidazo [4, 5-c] quinolin-4 (5H)-one derivatives, which exhibit a potent antiasthmatic activity, an unusual rearrangement was observed, where the methyl group migrates from the N-1 to the N-3 position on the imidazole during the reaction of Chapman rearrangement of 1-methyl-4-phenoxy-1H-imidazo [4, 5-c] quinoline 2.