Tetrahedron

Regiochemistry of mercury (II) oxide oxidation of unsymmetrical N, N-disubstituted hydroxylamines

SA Ali, SMA Hashmi, MN Siddiqui, MIM Wazeer

文献索引：Ali, Sk. Asrof; Hashmi, S. M. Azhar; Siddiqui, Mohammad N.; Wazeer, Mohammed I. M. Tetrahedron, 1996 , vol. 52, # 47 p. 14917 - 14928

全文：HTML全文

被引用次数: 34

摘要

Mercury (II) oxide oxidation of N, N-disubstituted hydroxylamines with the α and α′ carbon atoms containing one and two hydrogen atoms, respectively, gave aldonitrones in a highly regioselective manner. Removal of the α proton is involved in the rate determining step as shown by primary kinetic isotope effect.