Re (I) and 99m Tc (I) tricarbonyl complexes with ether-containing pyrazolyl-based chelators: Chemistry, biodistribution and metabolism

C Fernandes, L Maria, L Gano, IC Santos…

文献索引：Santos, Isabel; Fernandes, Celia; Maria, Leonor; Gano, Lurdes; Santos, Isabel C.; Paulo, Antonio Journal of Organometallic Chemistry, 2014 , vol. 760, p. 138 - 148

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被引用次数: 2

摘要

Abstract Tris (pyrazolyl) methane chelators, L1–L3, containing one or two ether groups at different positions of the azole rings, were synthesized and fully characterized. These chelators enabled the synthesis of fac-[99m Tc (CO) 3 {HC [4-(ROCH 2) pz] 3}]+(R= Me (Tc1), Et (Tc2)) and fac-[99m Tc (CO) 3 {HC [3, 5-(EtOCH 2) 2 pz] 3}]+(Tc3) which were identified by HPLC in comparison with the rhenium counterparts. The evaluation of Tc1– ...