Abstract Tris (pyrazolyl) methane chelators, L1–L3, containing one or two ether groups at different positions of the azole rings, were synthesized and fully characterized. These chelators enabled the synthesis of fac-[99m Tc (CO) 3 {HC [4-(ROCH 2) pz] 3}]+(R= Me (Tc1), Et (Tc2)) and fac-[99m Tc (CO) 3 {HC [3, 5-(EtOCH 2) 2 pz] 3}]+(Tc3) which were identified by HPLC in comparison with the rhenium counterparts. The evaluation of Tc1– ...