A mixture of 16 g. (0.11 mole) of sodium benzoate in 40 ml. of water was made slightly acid to litmus with 10% hydrochloric acid and then 200 ml. of ethylene glycol was added, together with 20.5 g. (0.1 mole) of 2-bromoacetyl- thiophene. After refluxing for twelve hours, the cooled mixture was poured into an excess of 4% sodium bicarbon- ate solution with stirring, causing the separation of a solid which was removed by filtration. The precipitate was washed thoroughly with ...
