One-pot synthesis of 2, 4, 5-trisubstituted imidazoles using MoO3/SiO2, an efficient and recyclable catalyst

…, SL Pandhare, TV Kotbagi, SB Umbarkar…

文献索引：Bhosale, Sidhanath V.; Kalyankar, Mohan B.; Nalage, Santosh V.; Bhosale, Dattatry S.; Pandhare, Swati L.; Kotbagi, Trupti V.; Umbarkar, Shubhangi B.; Dongare, Mohan K. Synthetic Communications, 2011 , vol. 41, # 5 p. 762 - 769

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被引用次数: 19

摘要

Abstract A simple one-pot synthesis has been developed for the synthesis of 2, 4, 5- trisubstituted imidazoles using an efficient and recyclable MoO3/SiO2 solid acid catalyst by condensation of benzil or benzoin, benzaldehyde, and ammonium acetate in acetonitrile as a solvent. Using this solid catalyst, the reactions could be carried out under mild reaction conditions with very good yield of imidazoles, up to 95%. This catalyst could be recycled ...