Diethyl N-benzyl-dl-aspartate (IV), needed in cording to the procedure of Reppe and Ufer2 and these laboratories for other syntheses] has been the product was esterified without isolation to prepared by several routes. give a 20% over-all yield of N-carbethoxymethyl It was thought that a convenient synthesis of IV aspartate. might be realized by the condensation of benzyl- It was noted that Warren and Grose4 reported amine with maleic ...
