Tetrahedron Letters

Copper-catalyzed aerobic oxidation of alcohols under fluorous biphasic conditions

B Betzemeier, M Cavazzini, S Quici, P Knochel

文献索引：Betzemeier, Bodo; Cavazzini, Marco; Quici, Silvio; Knochel, Paul Tetrahedron Letters, 2000 , vol. 41, # 22 p. 4343 - 4346

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被引用次数: 204

摘要

A catalytic amount of perfluoroalkyl substituted bipyridine 1 (2 mol%), CuBr· Me2S (2 mol%) and TEMPO (3.5 mol%) allow the oxidation of various alcohols to aldehydes and ketones in a fluorous biphasic system of chlorobenzene and perfluorooctane directly with oxygen. The catalyst can be used for several reaction runs without a loss of reactivity.