Application of Flow Chemistry to the Selective Reduction of Esters to Aldehydes

…, J Alcázar, A de la Hoz, A Díaz??Ortiz

文献索引：De Munoz, Juan M.; Alcazar, Jesus; De La Hoz, Antonio; Diaz-Ortiz, Angel European Journal of Organic Chemistry, 2012 , # 2 p. 260 - 263

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被引用次数: 5

摘要

Abstract The reduction of esters to aldehydes is an important transformation in organic chemistry and several reducing agents have been described. However, the use of this reaction in medicinal and natural product chemistry is limited due to the instability of the intermediates and the high reactivity of the reaction products. In the current article, the general and selective reduction of esters with diisobutyl-tert-butoxyaluminum hydride in ...