Click Chelators for Platinum??Based Anticancer Drugs

…, P Serafin, M Traikia, E Debiton, V Thery…

文献索引：Maisonial, Aurelie; Serafin, Patrycja; Traikia, Mounir; Debiton, Eric; Thery, Vincent; Aitken, David J.; Lemoine, Pascale; Viossat, Bernard; Gautier, Arnaud European Journal of Inorganic Chemistry, 2008 , # 2 p. 298 - 305

全文：HTML全文

被引用次数: 40

摘要

Abstract Triazoles from “click chemistry” are convenient ligands for the formation of platinum complexes bearing combined triazole–amine or triazole–carboxylate moieties. Striking differences in the chelation modes are observed between the two series. One of the triazole– amine platinum complexes exhibits selective cytotoxicity against breast cancer cells lines.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)