The Journal of Organic Chemistry

Cope rearrangements in the thiophene series

DWH MacDowell, JM Purpura

文献索引：MacDowell, Denis W. H.; Purpura, Joseph M. Journal of Organic Chemistry, 1986 , vol. 51, # 2 p. 183 - 188

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被引用次数: 12

摘要

The inability to observe Cope rearrangment at elevated temperatures for diethyl a- allylphenylmal~ nate~ does not extend to the analogous systems resulting from replacement of the benzene ring by 2-and 3-thiophene nuclei. Thermal rearrangement of diethyl a-allyl-2- thienylmalonate (5) at 250-260 OC for 12 h produces the expected Cope rearrangement product diethyl (3-allyl-2-thieny1) malonate (6)(49%) accompanied by ethyl 6-carboeth- ...