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Bioorganic & Medicinal Chemistry Letters 2007-11-15

Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors.

Sébastien Guery, Philipp Floersheim, Klemens Kaupmann, Wolfgang Froestl

文献索引:Bioorg. Med. Chem. Lett. 17(22) , 6206-11, (2007)

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摘要

The optimization of GS39783 into potent, selective, and safe positive allosteric modulators of GABA(B) receptors is presented.

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