Novel synthesis of primary arylamides from aryl methyl ketone oxidations using iodine in aqueous ammonia

…, C Guadarrama, D Corona, E Cuevas-Yañez

文献索引：Angeles, Norma A.; Villavicencio, Felipe; Guadarrama, Carlos; Corona, David; Cuevas-Yanez, Erick Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 905 - 908

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被引用次数: 10

摘要

Currently, one employed method to prepare aryl and heteroaryl amides involves the haloform cleavage reaction of trihalo acetyl derivatives. 2-5 However, these procedures require anhydrous conditions and, in some cases, expensive reagents such as trichloroacetyl chloride for preparing the trichloroketone starting material. 6-7 In addition, the use of water is preferred in environmental friendly procedures, which makes the chemical processes economical. 8 These ...