Organic Letters 2005-05-12

Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.

Benedek Vakulya, Szilárd Varga, Antal Csámpai, Tibor Soós

文献索引：Org. Lett. 7 , 1967-1969, (2005)

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摘要

Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.