Tetrahedron Letters

Synthesis of aza-Henry products and enamines in water by Michael addition of amines or thiols to activated unsaturated compounds

A Ziyaei-Halimehjani, MR Saidi

文献索引：Ziyaei-Halimehjani, Azim; Saidi, Mohammad R. Tetrahedron Letters, 2008 , vol. 49, # 7 p. 1244 - 1248

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被引用次数: 78

摘要

There are a few reports in the literature on reactions catalyzed by water without using any catalyst, such as the Michael addition of thiols to unsaturated compounds, 2 ring opening of epoxides by amines, 3 the synthesis of dithiocarbamate, 4 and N-tert-butyloxy-carbonylation of amines. 5 Recently, Ranu and Banerjee investigated the Michael addition of amines to α,β-unsaturated alkenes in water. 6 They showed that the reaction of aliphatic amines with activated ...