A Versatile Thiouronium??Based Solid??Phase Synthesis of 1, 3, 5??Triazines

KH Kong, CK Tan, X Lin, Y Lam

文献索引：Kong, Kah Hoe; Tan, Chong Kiat; Lin, Xijie; Lam, Yulin Chemistry - A European Journal, 2012 , vol. 18, # 5 p. 1476 - 1486

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被引用次数: 6

摘要

Abstract A thiouronium-based solid-phase synthesis of a 1, 3, 5-triazine scaffold has been developed. The key feature of the synthesis is the use of a readily accessible solid- supported thiouronium salt as a primary precursor for the stepwise assembly of the 1, 3, 5- triazine substrate. The sulfur linker employed in the synthesis is stable under both acidic and basic conditions and is versatile enough to provide access to monocyclic, bicyclic, and ...