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Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases

P Wipf, DC Aslan, EC Southwick, JS Lazo

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 3 p. 313 - 317

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被引用次数: 23

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 1 As part of a program to develop phosphatase inhibitors as mechanistic probes in cell biology and as potential antiproliferative agents, 2, 3 and 4 we have used combinatorial chemistry strategies to develop pharmacophores 1 and 2 ...